Mastectomies Chosen Despite Lack of Evidence

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The number of women having both breasts removed after a tumor is found in one increased by 150% over a five-year period despite a lack of evidence showing that double-mastectomies increase survival in most women, researchers reported yesterday.

Current guidelines for treatment of a localized breast cancer call only for removal of the tumor and not for a mastectomy — much less a double mastectomy.

But an increasing number of women, particularly young white women, are pushing for the more aggressive procedure for reasons that are not totally clear, the researchers said.

They surmised that some women believe the health-care system did not detect their tumor early enough and that continued screening would not be effective, while others might have been traumatized by chemotherapy. Improvements in reconstructive surgery also have made a double mastectomy a more acceptable alternative. “If they are making this decision based on fear, and thinking that it will increase their survival, then that would concern me,” Dr. Julie Gralow of the University of Washington, a spokeswoman for the American Society of Clinical Oncology, said.

“But if they understand that it won’t necessarily improve their survival, and that emotionally it is the best thing for them, then we would have to support it,” Dr. Gralow, who was not involved in the study, said.

Dr. Benjamin Paz of the City of Hope Comprehensive Cancer Center in Southern California, however, finds the trend “alarming, because the goal of medicine is to help people live well with their organs.”

Dr. Paz, who was not involved in the study, attributes the trend in large part to the increasing use of MRI imaging, which shows many small lesions in breasts that weren’t observed before.

“A woman goes through this, and she feels that [the cancer] is spreading all over,” he said. “It is very difficult to explain to such a woman that she can be treated with breast conservation.”

An estimated 178,480 women will be diagnosed with breast cancer this year, according to the American Cancer Society, and about 40,460 will die of it.

Dr. Todd Tuttle of the University of Minnesota Medical School and his colleagues decided to perform the study because they had noticed an increasing incidence of double mastectomies but could find no data about the frequency of its occurrence.


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