Keyboardist and songwriter Richard Bell, who played with Janis Joplin, has died of cancer in a Toronto hospital. He was 61.

Bell died June 15 after a long battle with multiple myeloma, said his longtime friend and fellow musician, Colin Linden.

His work included stints with some of rock ‘n’ roll’s most legendary performers, including Joplin and The Band.

He began playing with Joplin’s Full Tilt Boogie Band in 1970 and appeared on “Pearl,” her posthumously released album. He later joined The Band as a keyboardist and played on their albums “Jericho,” “High on the Hog,” and “Jubilation.” As a studio musician, he played with artists such as Bob Dylan, Judy Collins, Joe Walsh, Paul Butterfield, The Cowboy Junkies, Bruce Cockburn, and Bonnie Raitt. In recent years he has been part of the Toronto jazz/blues group Pork Bellies Futures.

After being diagnosed about a year ago with cancer, he had rigorous treatment and, despite a very poor prognosis, was well enough this spring to work in studio in Nashville on a comeback album with The Flying Burrito Brothers. But his cancer returned.

“I’ve never known a finer musician and a finer man,” Mr. Linden said. “He had an insatiable thirst for knowledge and for life. At age 61, he played as well or better than he ever played.”

Bell was the son of esteemed Canadian conductor, musician, and educator, Dr. Leslie Bell. A child prodigy, Bell began playing the piano at age 4 and studied at Canada’s Royal Conservatory of Music.