ALBANY – Defending their right to make independent decisions, the two lawmakers who agreed Monday to block Mayor Bloomberg’s plan for a potential Olympic stadium in Manhattan are now in open disagreement on what should happen next.

The majority leader of the Senate, Joseph Bruno, told reporters yesterday that separate development projects in Manhattan should go forward simultaneously. The comments, which were made without provocation, undercut the primary reason the speaker of the Assembly, Sheldon Silver, cited two days earlier for declining to approve the stadium plan.

“I keep hearing and reading, ‘you gotta do the Lower East Side, you gotta do the World Trade Center, we need that as a priority,’ ” Mr. Bruno said. “Why can’t we do both? We should be developing the West Side and the World Trade Center in tandem, and the entire city and the entire state. There’s 19 million people in this state.”

In defeating the proposed $2.2 billion stadium on Manhattan’s far West Side, Mr. Bruno, a Republican whose district lies just east and north of Albany, found a partner in Mr. Silver, a Democrat whose district encompasses the World Trade Center site. The two men blocked a $300 million state subsidy for the project Monday, putting an end to months of speculation as to whether the stadium would be built.

Mayor Bloomberg, chief backer of the project, called the decision a blow to New York City, a blow to America’s chances of securing the 2012 Olympics, and a potential blow to the future of other large-scale development projects in the city.

“One of the great dangers is that developers are going to get disheartened and say, ‘I can’t build anything in New York City because the politics always get in the way,’ ” Mr. Bloomberg said.

Mr. Silver’s chief reason for opposing the stadium was the 24 million square feet of commercial office space planned for its perimeter. On Monday, he characterized the office space as unwelcome competition to the redevelopment of Lower Manhattan. He said developing the West Side while development downtown continues to languish would be a betrayal of the victims of the September 11, 2001, terrorist attacks.

“Ask the governor, ask the mayor, how they justify building 24 million square feet of commercial office space on the West Side, how they justify the incentives they are providing to attract businesses there in competition with Lower Manhattan,” Mr. Silver said before the meeting of the Public Authorities Control Board. “Developing the West Side and ignoring Lower Manhattan: This is what the vote is really about.”

Despite their disagreement on the future of Manhattan development, Messrs. Bruno and Silver both said yesterday that Mr. Bloomberg’s anger over the stadium should not trigger a game of political retribution. A report in the New York Post quoted an unnamed source as saying Mr. Bloomberg would probably cut off campaign contributions to members of the Senate majority as payback.

Mr. Bruno said he does not anticipate retribution. “I don’t expect that,” he said. “The mayor has enough good judgment to understand that life goes on. He has a job to govern, and we have a job to govern, and we’re just going to keep doing that, and I think we’re going to do a lot of good things together.”

Mr. Silver responded to speculation about potential retaliation by saying he has been an ally of Mr. Bloomberg on issues and that he does not believe in retribution.

“I would hope the mayor would recognize the fact that people have the right to disagree,” Mr. Silver said. “I was called upon to make a vote at a public forum where I had to vote, and that was done in that fashion. … I slept very well last night. I’m comfortable that I made the right decision on behalf of the people of the state of New York.”